Overview
A simplified, single-chain version of the hormone relaxin.
Relaxin softens and de-scars tissue (anti-fibrotic).
B7-33 aims to do that, reduce fibrosis in heart, liver, and kidney; in a peptide that’s easier to make.
Entirely research-stage, no human data.
What It Does
B7-33 is a single-chain analog of human relaxin-2 that selectively activates the RXFP1 receptor.
In animal models it reduces fibrosis markers and tissue scarring (liver, kidney, cardiac) comparably to native relaxin, with organ-protective, anti- fibrotic effects.
All evidence is preclinical.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 2 mg | + 0.4 mL | 5 mg/mL |
| 10 mg | + 2 mL | 5 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Research-derived | Daily | 100–500 mcg | SubQ. Animal-study-derived range only, no validated human dose or safety margin. |
| Off | variable | – | No established cycle, preclinical compound. Caution: B7-33’s entire evidence base is animal data. There is no clinically validated protocol, no approved human route, and no established safety margin. Doses here are research-derived and included for completeness only. Relaxin signaling affects the vasculature and connective tissue broadly. |
Relaxin analog, contraindicated in pregnancy (relaxin acts on the reproductive tract). Otherwise unisex; entirely preclinical.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F.
- Best used within ~2–4 weeks, kept cold (structure-based estimate, no published data); that is close to the 28- day sterility limit, so use whichever comes first.
- Unknown in humans.
- Animal data suggest anti-fibrotic, organ-protective effects; not demonstrated in people.
- Supply math 2mg → ~6 vials | 10mg → ~2 vials (4-wk @ 400 mcg/day, research-derived, not a recommendation)
