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Blends and Mixed Protocols

BR226

Relaxation PM, pre-bed sleep stack: GABA + melatonin + arginine + glutamine in one shot.

Research referenceCommunity compiled
Research & reference information

This profile compiles research and community-sourced reference information for educational purposes. Information may evolve as research and community knowledge develop. It is not individualized medical advice.

Overview

Relaxation PM, pre-bed sleep stack: GABA + melatonin + arginine + glutamine in one shot.

What It Does

Sleep / relaxation-stack injection.

GABA: inhibitory neurotransmitter; injectable bypass of poor BBB penetration is debated.

Reconstitution

Vial SizeBAC Water / SolventConcentration
10 mlSolution, no reconstitution neededGABA 10 mg/mL
Interactive tool

Reconstitution Calculator

Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.

Calculated concentration—Enter both values above.
Optional conversion

Enter a target amount you already have and select the syringe capacity.

Calculated draw—Enter concentration inputs and a target amount.

Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.

Protocol

PhaseFrequencyAmountNotes
Pre-bedNightly1 mLInject 30–60 min before sleep. Full vial = 10 nights.
Off1–2 weeks–Optional break after 8 weeks continuous to avoid melatonin receptor downregulation.
Cycle & Timing

4–8 weeks on / 1–2 weeks off, or as needed. Avoid daily continuous use beyond 8 weeks (melatonin receptor downregulation).

Timing

Daily SubQ, anytime;

Route / Related Reference

notes for compound-specific timing.

Population Considerations

Follows its components, same protocol for men and women; no meaningful cycle effect. Avoid in pregnancy.

Handling & Stacking

Injection site
SubQ abdomen or outer thigh.
Storage
  • Solution: refrigerate 36–46°F.
  • Use within 28 days.
  • Protect from light (melatonin photodegrades).
  • BR226 ships as a ready solution with no real community potency figure, so treat the opened vial as sterility-limited at ~28–30 days refrigerated at 36–46°F and keep it dark since the melatonin component photodegrades; no published data, so it's a best-guess default.
Side effects
Vivid dreams (melatonin), AM grogginess if dosed too close to wake. Rare flushing (arginine vasodilation).
What to expect
Drowsiness within 20–30 min. Deeper subjective sleep over 1–2 weeks of consistent pre-bed use.
Pairs well with
DSIP (additive sleep-architecture support); GHK-Cu (overnight repair); MOTS-c off-day stacking
Avoid
Stimulants pre-bed. Daytime alertness windows (causes drowsiness).

Safety & Patient Education

Labs
Compound-specific: CBC + CMP baseline; no compound-specific markers routinely required
References
PubMed · thepeptidereport