Overview
Your body’s own antimicrobial peptide (a cathelicidin).
It kills bacteria, including biofilms that resist antibiotics, and supports wound healing.
Used in research for stubborn infections and chronic wounds.
What It Does
LL-37 is the active fragment of human cathelicidin.
It disrupts bacterial membranes and biofilms, neutralizes endotoxin, and modulates immune/wound-healing responses (angiogenesis, re-epithelialization).
Because it also activates dendritic cells, it can aggravate autoimmune/inflammatory conditions; a key caution.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 5 mg | + 2.5 mL | 2 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–4 | 1–3×/week (or daily AM) | 100–200 mcg | SubQ, AM. Start low; injection-site reactions are common (mild inflammatory action). |
| Off | 2–4 weeks | – | Cycle to limit immune over-stimulation. |
4–6 weeks on / 2–4 weeks off.
morning SubQ; can be used locally near a wound/infection site under guidance. Caution: avoid systemic use if you have an autoimmune or chronic inflammatory condition.
Unisex antimicrobial peptide, same protocol for men and women, no cycle effect. Research-stage; avoid in pregnancy.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F.
- Best used within ~2–4 weeks, kept cold (structure-based estimate, no published data); that is close to the 28- day sterility limit, so use whichever comes first.
- Support for stubborn/biofilm infections and chronic wound healing in research settings.
- Not a replacement for prescribed antibiotics when those are indicated.
- Supply math 5mg → 1–2 vials (6-wk @ 200 mcg × 3/wk)
