Overview
The sleep/circadian hormone your pineal gland makes when it gets dark.
Signals “night” to the body.
Most people take it orally; this is an injectable form, for sleep timing and as an antioxidant.
What It Does
Melatonin is the pineal hormone that regulates the sleep-wake cycle and acts as a potent antioxidant.
It shifts circadian timing (useful for jet lag/shift work) and promotes sleep onset.
Oral is the usual route; injectable delivers a faster, more predictable dose.
Lower doses (0.5–1 mg) are often better for sleep than high doses.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 10 mg | + 5 mL | 2 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Nightly | Pre-bed | 0.5–3 mg | SubQ 30–60 min before bed. Start low, more is not better for sleep. |
as needed; can be used nightly or for jet-lag/shift-work resets.
30–60 min before desired sleep; for jet lag, time to the destination night. Note: low doses (0.5–1 mg) often work better and cause less morning grogginess than high doses.
Unisex, dose by protocol, not sex; start low. Discuss with a prescriber in pregnancy / breastfeeding.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F.
- Best used within 28 days.
- Protect from light.
- Melatonin's a small molecule with no real community potency figure once reconstituted, so treat sterility at ~28 days refrigerated as the practical limit and keep it dark since it photodegrades.
- Faster sleep onset and circadian shifting.
- Not a sedative, it signals timing, so a dark, low-stimulation environment matters.
- Supply math 10mg → 1 vial (weeks of nightly low-dose use)
