Overview
The same NAD+ as the standard page, but pH-buffered so it stings and flushes less.
Plain NAD+ injections are notoriously uncomfortable (burning, flushing, chest tightness if pushed fast); the buffered version makes the same dose far more tolerable.
What It Does
NAD Buffer is NAD+ (nicotinamide adenine dinucleotide) formulated at a more physiological pH.
NAD+ is the central coenzyme of cellular energy and sirtuin/DNA-repair pathways; buffering reduces the acidity-driven injection discomfort and flushing without changing the active molecule.
Same uses as NAD+, energy, recovery, longevity; with better tolerability.
See the NAD+ page for full background.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 500 mg | + 1 mL | 500 mg/mL |
| 1000 mg | + 2 mL | 500 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–2 (ramp) | 2–3×/week | 25–50 mg | SubQ, injected SLOWLY. Buffering helps, but slow is still key. |
| Weeks 3+ | 2–3×/week | 50–100 mg | Titrate up by tolerance. Still inject slowly to minimize flushing. |
ongoing or 8–12 week blocks.
daytime (can be energizing). Key: the buffer reduces discomfort, but slow injection remains the main way to avoid the flush/chest-tightness; never push a bolus.
N/A, a buffer / reagent for reconstitution, not a dosed compound.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F.
- Best used within 28 days.
- Protect from light.
- NAD buffer is just pH-adjusted NAD+, so it fades the way NAD+ does; the honest limit is potency at ~10–14 days refrigerated and dark (glycosidic and pyrophosphate hydrolysis), well before the 28-day sterility cap, matching this guide's NAD+ page.
