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Cognitive and Neuroprotective

Selank (Intranasal)

Selank as a nasal spray.

Research referenceCommunity compiled
Research & reference information

This profile compiles research and community-sourced reference information for educational purposes. Information may evolve as research and community knowledge develop. It is not individualized medical advice.

Overview

Selank as a nasal spray.

What It Does

Anxiolytic nootropic, Russian pharmaceutical for anxiety and cognitive enhancement.

Approved in Russia for anxiety disorders.

Tuftsin analog modulating GABAergic and serotonergic systems.

Inhibits enkephalin-degrading enzymes.

Stimulates BDNF and NGF.

Reconstitution

Vial SizeBAC Water / SolventConcentration
5 mg+ 5 mL sterile saline1 mg/mL
10 mg+ 10 mL sterile saline1 mg/mL
Interactive tool

Reconstitution Calculator

Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.

Calculated concentration—Enter both values above.
Optional conversion

Enter a target amount you already have and select the syringe capacity.

Calculated draw—Enter concentration inputs and a target amount.

Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.

Protocol

PhaseFrequencyAmountNotes
StandardDaily AM200–400 mcg1–2 sprays per nostril, alternating sides. 100 µL @ 1 mg/mL = 100 mcg per spray.
HigherDaily AM600 mcg3 sprays per nostril, alternating sides. Or split AM + early afternoon to reduce nasal irritation.
Off1–2 weeks–Tolerance prevention. 5-day-on / 2-day-off variant also community-standard.
Cycle & Timing

4–6 weeks on, 2 weeks off.

Timing

AM intranasal, calibrate sprays with the supplier’s nasal pump (standard 100 µL per actuation) before clinical use.

Evidence Context

Russian-approved (anxiety); no completed Western clinical trials.

Population Considerations

Unisex anxiolytic nootropic (intranasal), no sex or cycle effect; dose by protocol. Avoid in pregnancy.

Handling & Stacking

Injection site
  • Intranasal: 1–2 sprays per nostril, alternating sides each dose.
  • Use a calibrated nasal pump (100 µL/spray, 100 mcg per spray at this recon) and tilt head slightly back during instillation.
  • For SubQ injection, see the Selank page.
Storage
  • Freeze-dried: -4°F.
  • Reconstituted in saline: 36–46°F.
  • Best used within 21 days.
  • Discard if cloudy or particulate.
  • Community runs Selank nasal spray about ~1–2 weeks when mixed in plain saline (or ~3–4 weeks if made with bacteriostatic water) refrigerated at 36–46°F and kept dark; the saline-versus-BAC split is community convention, not published data, so treat it as an estimate.
Side effects
Mild sedation or relaxation. Rarely: headache. Generally very well tolerated.
What to expect
  • Anxiolytic effect within 20–30 min of intranasal.
  • Clear-headed calmness, not sedating.
  • Memory and focus improvement over 2–4 weeks.
  • No addiction or withdrawal.
  • Supply math 5mg → 4 vials | 10mg → 2 vials (4-wk @ 600 mcg × 7/wk)
Pairs well with
Semax (synergistic nootropic / mood support); BPC-157 (neuroregeneration); GHK-Cu (neuroprotective complement); L-Theanine (calming amplification)
Avoid
MAOIs (theoretical serotonergic interaction). Active psychosis / bipolar mania
Approved drug
  • For anxiety the approved options are SSRIs (sertraline, escitalopram), SNRIs (venlafaxine, duloxetine) and buspirone; all with large trial bases.
  • This peptide has no Western approval or RCT.

Safety & Patient Education

Labs
Compound-specific: CBC + CMP baseline; no compound-specific markers routinely required
References
PubMed · thepeptidereport