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Longevity and Bioregulators

VESUGEN

A short peptide bioregulator (Khavinson) aimed at the vascular system, blood vessels. Part of the model that aging happens along three tracks (cellular, immune, vascular); Vesugen targets the vascular track in brief courses.

Research referenceCommunity compiled
Research & reference information

This profile compiles research and community-sourced reference information for educational purposes. Information may evolve as research and community knowledge develop. It is not individualized medical advice.

Overview

A short peptide bioregulator (Khavinson) aimed at the vascular system, blood vessels.

Part of the model that aging happens along three tracks (cellular, immune, vascular); Vesugen targets the vascular track in brief courses.

What It Does

Vesugen is a Khavinson tripeptide (Lys-Glu-Asp, KED) targeting vascular tissue.

It is proposed to support healthy endothelial/vascular gene expression and function.

Evidence is largely from Russian bioregulator research; used as short pulsed courses.

Reconstitution

Vial SizeBAC Water / SolventConcentration
10 mg+ 5 mL2 mg/mL
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Protocol

PhaseFrequencyAmountNotes
Course (10–20 days)Daily1–2 mg SubQSubQ. (Oral bioregulator capsules dose higher.)
Between courses––1–3 courses per year.
Cycle & Timing

10–20 day course, 1–3×/year.

Timing

any time. Note: vascular-targeted bioregulator; evidence is largely Russian research, limited Western RCTs.

Population Considerations

Unisex peptide bioregulator, short courses, no sex-specific dosing; minimal human data. Avoid in pregnancy.

Handling & Stacking

Injection site
SubQ, abdomen. Rotate.
Storage
Freeze-dried: -4°F. Reconstituted: 36–46°F, best used within ~4–6 weeks (structure-based estimate), which covers the usual course.
Side effects
Generally well tolerated, mild injection-site reaction. Human safety data limited.
What to expect
Proposed vascular support over a course; subtle, preliminary evidence. Supply math 10mg → 4 vials (20-day course @ 2 mg/day SubQ)
Pairs well with
Other Khavinson bioregulators (cellular/immune/vascular triad); Epithalon; Thymalin
Avoid
Active malignancy (theoretical gene-expression effects). Pregnancy

Safety & Patient Education

Contraindications
Active malignancy (theoretical, tissue gene-expression modulation) Pregnancy and lactation Hypersensitivity to the peptide
Warnings
Limited Western clinical data, most evidence is Russian research Quality varies, request a COA Subtle, course-based effects
Drug interactions
No well-characterized interactions Commonly stacked with other bioregulators in a course
Labs
None compound-specific; vascular/blood-pressure tracking if that’s the goal
Stop criteria
Persistent injection-site reaction Any unexpected cardiovascular or systemic symptom Pregnancy
Patient education
A short-course, vascular-targeted bioregulator; not continuous Evidence is preliminary and largely Russian Subtle effects; manage expectations Request a COA; source quality matters
References
researchdosing · peptidedosages · PubMed · thepeptidereport