Overview
AOD-9604 is a synthetic peptide fragment representing the lipolytic C-terminal region (amino acids 176–191) of human growth hormone, modified with an added tyrosine.
What problem it targets: It is researched for targeted body fat reduction, lipolysis enhancement, and metabolic optimization without the unwanted side effects of full-length growth hormone.
What It Does
• Ignites fat breakdown (lipolysis): Mimics the natural fat-burning activity of human growth hormone by activating beta-3 adrenergic pathways and mobilizing stored triglycerides.
• Inhibits new fat formation (lipogenesis): Signals fat cells to halt the conversion of circulating calories into stored fatty tissue, helping prevent fat regain.
• Zero impact on blood sugar or IGF-1: Because it isolates only the fat-burning sequence of HGH, it does not elevate insulin, cause insulin resistance, or trigger systemic tissue growth.
• Realistic expectations: AOD-9604 acts as an accelerator for fat mobilization rather than a stand-alone miracle; it produces optimal results when paired with a calorie deficit and cardiovascular activity.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 2 mg | 2ml | 1 mg/mL |
| 5 mg | 2ml | 2.5 mg/mL |
| 10 mg | 2ml | 5 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Solubility & Preparation Notes
The C-terminal region of growth hormone is lipophilic/hydrophobic. In plain neutral BAC water, the powder frequently clumps into a gel-like ring or produces a cloudy, milky suspension that won’t dissolve.
Solution: Reconstituting first with sterile 0.6% acetic acid breaks the electrostatic aggregation immediately, resulting in a completely crystal-clear liquid.
Step 1 — Solubilize (The Acid Step):
Draw 0.5 mL of sterile 0.6% acetic acid.
Inject it slowly down the inside glass wall of the vial (never spray directly onto the lyophilized cake).
Gently roll the vial between your palms until the liquid is 100% crystal clear.
Verification: Do not add BAC water while the solution is still hazy or clumped. It must be completely transparent first.
Step 2 — Dilute (The BAC Water Top-Off):
Once completely dissolved and clear, add the remaining volume of standard Bacteriostatic Water required by your dosing math.
Why this works: The acetic acid establishes the charge state needed to break the peptide apart into solution; the remaining BAC water dilutes the acid concentration down so it will not sting or irritate tissue upon injection.
Step 3 — Note on reconstituting the entire vial with Acetic Acid:
Users can choose to reconstitute the entire vial using only 0.6% acetic acid if they prioritize maximum long-term chemical stability (standard practice for extended IGF-1 storage). However, note that injecting an unbuffered, full-acid solution will cause a noticeable local sting and burning sensation at the injection site.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–8 | Daily (5 on / 2 off) | 300 mcg | AM, fasted, into abdominal fat. 300–500 mcg range; 300 is standard. |
| Off | 4–8 weeks | – | Weekly 2-day break during the cycle helps avoid receptor desensitization. |
8–12 weeks on (5 days on / 2 off each week) / 4–8 weeks off.
first thing AM on an empty stomach, fasted state favors fat oxidation. Note: does not raise IGF-1 or glucose, so it lacks the GH-class metabolic warnings.
Unisex (a GH fragment for fat loss without GH’s growth signaling), same protocol for men and women, no cycle effect. Avoid in pregnancy.
Handling & Stacking
- Subtle, gradual fat-loss support over 8–12 weeks; best as an adjunct to diet/training or stacked with a GLP-1 or GH peptide, not a standalone fix.
- Supply math 2mg → 6 vials | 5mg → 3 vials | 10mg → 2 vials (8-wk @ 300 mcg, 5/wk)
