Overview
A pre-mixed combination of two different growth hormone stimulators that work via separate pathways, producing a synergistic pulse that’s stronger than either alone; without increasing cortisol or appetite.
What It Does
Pre-mixed GHRH + GHRP stack, amplified, synergistic GH pulse from two different receptor pathways in one injection.
CJC-1295 (No DAC) stimulates GHRH receptors.
Ipamorelin activates GHS-R1a ghrelin receptors.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 10 mg | + 3 mL | 3.33 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–2 | Nightly pre-bed | 200 mcg | Start low and assess how your body responds before increasing. |
| Weeks 3–12 | Nightly pre-bed | 400 mcg | Standard effective dose for most users. |
| Off | 4 weeks | – | Off period, let your pituitary and receptors recover before the next cycle. |
12 weeks on / 4 weeks off. Max 16 weeks on / 4–8 weeks off; receptor desensitization beyond 16 weeks continuous.
Fasted, pre-bed is standard; the pulse lands with the natural deep-sleep GH release, which is why this stack is the go-to for sleep + recovery. No food 90 min before / 60 min after; fasted AM works if pre-bed is impractical. Sleep: GHRH promotes slow-wave sleep, most notice deeper sleep in 1–2 weeks.
Women make ~3× the GH of men yet have similar IGF-1, they’re less responsive, so often need a higher dose to move IGF-1. Oral estrogen blunts IGF-1 further (read it as running low); a skin patch/gel is more predictable. Men: Men convert GH to IGF-1 more efficiently and more often overshoot the age ceiling (a higher malignancy signal), aim mid-normal for age, don’t chase the Women make ~3× the GH of men yet have similar IGF-1, they’re less responsive, so often need a higher dose to move IGF-1. Oral estrogen blunts IGF-1 further (read it as running low); a skin patch/gel is more predictable. Men: Men convert GH to IGF-1 more efficiently and more often overshoot the age ceiling (a higher malignancy signal), aim mid-normal for age, don’t chase the top.
Handling & Stacking
Safety & Patient Education
- Compound-specific: IGF-1 (baseline + Week 8 + end), Lipid panel (Week 0/12) IGF-1 at baseline, mid-cycle, and end of cycle.
- Target ULN for age Fasting glucose and HbA1c at baseline and end of cycle Mammogram and prostate screening per age-appropriate guidelines before starting Out of range?
- IGF-1 above your age range = too much growth signal (feeds hidden cancer, enlarges organs) → drop the dose; rising glucose/HbA1c = sugar creeping up.
