Overview
The long-acting version of CJC-1295.
One injection lasts about a week because it grabs onto a blood protein (albumin).
Instead of a single sharp pulse, it raises your GH/IGF-1 baseline for days; convenient, but less “natural” than the No-DAC pulse.
What It Does
CJC-1295 DAC is a GHRH analog with a Drug Affinity Complex that binds reversibly to albumin, extending half-life from minutes (No-DAC) to ~6– 8 days.
This produces a sustained elevation of GH and IGF-1 (a continuous “bleed”) rather than the pulsatile release of the No-DAC version.
Convenient weekly dosing; the trade-off is loss of natural GH pulsatility.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 2 mg | + 1 mL | 2 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–2 | Once weekly | 1 mg | Start at the low end; the long half-life means levels build over the first 1–2 weeks. |
| Weeks 3–12 | Once weekly (or split 2×/wk) | 2 mg/week | Standard. Splitting into 2 doses/week smooths levels and side effects. |
| Off | 4 weeks | – | Let IGF-1 normalize before re-cycling. |
8–12 weeks on / 4 weeks off.
Any time of day (long half-life makes timing far less critical than No-DAC). Pair with a GHRP if a stronger pulse is wanted. DAC vs No-DAC: DAC = convenience + sustained levels; No-DAC = physiological pulses. Many prefer No-DAC for a more natural profile.
Women make ~3× the GH of men yet have similar IGF-1, they’re less responsive, so often need a higher dose to move IGF-1. Oral estrogen blunts IGF-1 further (read it as running low); a skin patch/gel is more predictable. Men: Men convert GH to IGF-1 more efficiently and more often overshoot the age ceiling (a higher malignancy signal), aim mid-normal for age, don’t chase the Women make ~3× the GH of men yet have similar IGF-1, they’re less responsive, so often need a higher dose to move IGF-1. Oral estrogen blunts IGF-1 further (read it as running low); a skin patch/gel is more predictable. Men: Men convert GH to IGF-1 more efficiently and more often overshoot the age ceiling (a higher malignancy signal), aim mid-normal for age, don’t chase the top.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F.
- Best used within ~2–4 weeks, kept cold (structure-based estimate, no published data); that is close to the 28- day sterility limit, so use whichever comes first.
- Avoid freeze-thaw.
Safety & Patient Education
- IGF-1 (baseline + Week 4 + Week 8 + end), sustained levels make monitoring more important Fasting glucose / HbA1c (baseline + end) Age-appropriate cancer screening before starting Out of range?
- IGF-1 above your age range = too much growth signal (feeds hidden cancer, enlarges organs) → drop the dose; rising glucose/HbA1c = sugar creeping up.
