Overview
The original ghrelin-mimetic GH-releaser.
Same GH-boosting mechanism as GHRP-2 but with a much stronger appetite kick, favored when the goal is eating more and gaining.
What It Does
GHRP-6 is a GHS-R1a (ghrelin receptor) agonist that triggers a GH pulse and powerfully stimulates hunger.
Mild cortisol and prolactin rise.
Combined with a GHRH analog (Sermorelin/CJC) the GH release is far larger than either alone.
The strong appetite makes it a bulking-phase tool and a less ideal choice when cutting.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 5 mg | + 1 mL | 5 mg/mL |
| 10 mg | + 2 mL | 5 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Weeks 1–2 | 2×/day | 100 mcg | Expect strong hunger ~20–30 min after dosing. AM fasted + pre-bed. |
| Weeks 3–12 | 2–3×/day | 200 mcg | Working dose. ~1 mcg/kg saturates the GH response; more mainly adds cortisol/prolactin. |
| Off | 4 weeks | – | Prevents ghrelin-receptor downregulation. |
8–12 weeks on / 4 weeks off.
Empty stomach, no food 30 min after. The hunger surge is the tell that it’s working (and why it suits bulking). Saturation: plateaus ~1 mcg/kg.
Women need more GH but get a bigger bump from ghrelin-types, though these raise prolactin, which can disrupt cycles/ovulation (watch for missed periods). Oral estrogen blunts IGF-1. Men: Men overshoot the IGF-1 ceiling more easily (aim mid-normal); high prolactin lowers libido and testosterone, switch to a cleaner option if it cli Women need more GH but get a bigger bump from ghrelin-types, though these raise prolactin, which can disrupt cycles/ovulation (watch for missed periods). Oral estrogen blunts IGF-1. Men: Men overshoot the IGF-1 ceiling more easily (aim mid-normal); high prolactin lowers libido and testosterone, switch to a cleaner option if it climbs.
Handling & Stacking
- Strong appetite and improved sleep early; recovery and body-composition gains over 8–12 weeks.
- Best in a GHRH + GHRP stack during a gaining phase.
- Supply math 5mg → 7 vials | 10mg → 4 vials (12-wk @ 200 mcg × 2/day)
Safety & Patient Education
- IGF-1 (baseline + Week 8 + end) Fasting glucose / HbA1c (baseline + end), especially given appetite effect Prolactin if symptomatic Age-appropriate cancer screening before starting Out of range?
- IGF-1 above your age range = too much growth signal (feeds hidden cancer, enlarges organs) → drop the dose; rising glucose/HbA1c = sugar creeping up.
