Overview
The growth signal that GH normally creates downstream. Injecting it directly skips a step. Tanks blood sugar, eat carbs with it.
What It Does
Standard insulin-like growth factor 1, the natural form with a 12–15 min half-life. Binds IGF-1 receptor (IGF-1R) on muscle cells to activate PI3K/AKT and MAPK/ERK pathways, promoting protein synthesis, satellite cell activation.
Reconstitution
| Vial Size | BAC Water / Solvent | Concentration |
|---|---|---|
| 1 mg | + 2.5 mL | 0.4 mg/mL |
Reconstitution Calculator
Enter the vial amount and diluent volume to calculate concentration. If you already have a target amount, you can also convert it to liquid volume and syringe markings. This tool does not recommend a target amount.
Enter a target amount you already have and select the syringe capacity.
Mathematical reference only. The calculator does not determine an appropriate target amount. Syringe capacity only changes the maximum volume that fits.
Protocol
| Phase | Frequency | Amount | Notes |
|---|---|---|---|
| Entry | Post-workout daily | 20–40 mcg | Start here. Assess hypoglycemia response before increasing. |
| Working | Post-workout daily | 60–80 mcg | Community working dose. Have fast carbs available. |
| Max | Post-workout daily | 100 mcg | Upper community range. Do not exceed without monitoring. |
| Off | 4 weeks | – | Receptor sensitivity reset. |
4–6 weeks on, 4 weeks off. Short cycles only.
With food, fast-acting carbs available; never fasted (hypoglycemia risk).
Direct IGF-1 bypasses GH, so estrogen doesn’t soften it; same growth-signal caution: breast, ovarian, or uterine history. Men: Same growth-signal caution, prostate; watch PSA in men over Direct IGF-1 bypasses GH, so estrogen doesn’t soften it; same growth-signal caution: breast, ovarian, or uterine history. Men: Same growth-signal caution, prostate; watch PSA in men over ~40.
Handling & Stacking
- Freeze-dried: -4°F.
- Reconstituted: 36–46°F, best used within ~10–14 days (structure-based estimate, no published data); potency fades before the 28- day sterility limit, so keep it cold and use it promptly.
- Local anabolic response at the injection site within minutes; systemic effect minimal (rapid IGFBP binding).
- Muscle fullness/pump lasts 1–2 h.
- Supply math 1mg → 3 vials (4-wk @ 80 mcg × 7/wk)
Safety & Patient Education
- IGF-1 (baseline / Wk 8 / end; you're dosing it directly, so this tracks exposure), Fasting glucose (Wk 0/4/8) Lipid panel (Wk 0/12) Hip/scoliosis exam in pediatrics Out of range?
- IGF-1 above your age range = too much growth signal → drop the dose.
- Hypoglycemia is the real acute risk – IGF-1 is insulin-like and can crash blood sugar, so dose with food/carbs and keep fast sugar on hand; shaky, sweaty, or foggy after a dose = treat it, don't wait.
- Vials must be refrigerated never frozen (somatropin) Rotate injection sites Report headaches with nausea/vision changes immediately Report new joint pain Children: report any limp or hip/knee pain immediately Always have fast-acting carbs available before injection.
- Do not inject and skip a meal.
