The BPC-157 and TB-500 blend dosage question has a catch built into it: once the two compounds are in the same vial, you cannot adjust one without the other. That makes the ratio — not the dose — the number that actually controls your protocol. This page works through the blend maths, the reconstitution figures for both vial sizes, and what the 1:1 ratio means for each compound's schedule.
Quick Breakdown: BPC-157 + TB-500 Blend Dosage
Quick Answer: The blend is supplied 1:1 by mass — 10 mg (5 mg + 5 mg) or 20 mg (10 mg + 10 mg). Reconstituting a 20 mg vial with 4 mL gives 5 mg/mL combined; a 20-unit draw then delivers 1 mg total, 500 mcg of each compound. Research protocols for the individual compounds run BPC-157 at 250–500 mcg once or twice daily and TB-500 at 2–2.5 mg twice weekly — which is why a fixed 1:1 blend forces a compromise on one of them.| Term | Figure | What It Means |
|---|---|---|
| Blend ratio | 1:1 by mass | Equal milligrams of each compound — fixed at manufacture. |
| 10 mg vial | 5 mg + 5 mg | Half the mass is each compound. |
| 20 mg vial | 10 mg + 10 mg | Note: 20 mg total, not 20 mg of each. |
| Concentration | 5 mg/mL at 4 mL | For a 20 mg vial — 50 mcg per unit combined, 25 mcg of each. |
The Blend Arithmetic, Both Vials
Every calculation runs on the total mass first, then splits by the ratio. Getting that order wrong is what produces vials that are twice as concentrated as intended.
| Vial | Diluent | Combined Concentration | Per Unit | Each Compound |
|---|---|---|---|---|
| 10 mg | 2.0 mL | 5 mg/mL (5,000 mcg/mL) | 50 mcg | 25 mcg |
| 10 mg | 4.0 mL | 2.5 mg/mL (2,500 mcg/mL) | 25 mcg | 12.5 mcg |
| 20 mg | 4.0 mL | 5 mg/mL (5,000 mcg/mL) | 50 mcg | 25 mcg |
| 20 mg | 2.0 mL | 10 mg/mL (10,000 mcg/mL) | 100 mcg | 50 mcg |
At 5 mg/mL combined, a 500 mcg dose of each compound is a 20-unit draw. At 10 mg/mL — half the diluent — the same 20 units delivers double, which is the mistake that matters most with blends. For the general conversion, see how much bacteriostatic water to add or use the Peptide Calculator.
Why the 1:1 Ratio Forces a Compromise
The two compounds have different research schedules:
- BPC-157 is studied at 250–500 mcg per administration, often once or twice daily — small, frequent dosing.
- TB-500 is studied at 2–2.5 mg per administration, typically twice weekly — much larger, less frequent dosing.
In a 1:1 vial, every unit contains equal mass of both. Land the draw on BPC-157's typical range and TB-500 is under-delivered by an order of magnitude; match TB-500 and BPC-157 is well above its studied range. That is not a flaw in the product — it is what a fixed ratio means. If your protocol needs independent control of each compound, separate vials are the only way to get it. The blend is for research where both mechanisms are wanted together at the same mass.
BPC-157 vs TB-500: Which Schedule Wins
| Question | BPC-157 | TB-500 |
|---|---|---|
| Typical research amount | 250–500 mcg per administration. | 2–2.5 mg per administration. |
| Cadence | Once or twice daily. | Twice weekly. |
| Mechanistic focus | Angiogenesis, VEGFR2 signalling, fibroblast activity. | Actin sequestration, cell migration, vascular remodelling. |
| Standalone vial price | $35 (5 mg) · $50 (10 mg). | Sold in blends and bundles. |
For the mechanism detail: BPC-157 research guide and TB-500 research guide. If you are weighing the blend against the individual compounds, the Wolverine blend ratios breakdown covers the composition question.
What the Blend Costs
| Vial | Price | Per Milligram | Composition (1:1) |
|---|---|---|---|
| 10 mg | $50 | $5.00 / mg | 5 mg BPC-157 + 5 mg TB-500 |
| 20 mg | $90 | $4.50 / mg | 10 mg BPC-157 + 10 mg TB-500 |
Neither compound is an approved medicine, so there is no prescription route to compare against — no pharmacy shelf, no insurer, no waiting list. The vial is the access. See the Wolverine blend product page for current stock.
Frequently Asked Questions
How much of a BPC-157 and TB-500 blend should be drawn per day?
It depends which compound's schedule you are following, because the 1:1 ratio prevents satisfying both at once. At 5 mg/mL combined, a 20-unit draw delivers 500 mcg of each — the top of BPC-157's range and a fraction of TB-500's.
Is a 20 mg blend 20 mg of each compound?
No. It is 20 mg total, 10 mg of each at a 1:1 ratio.
How much BAC water for a 20 mg blend?
4 mL gives 5 mg/mL combined, which keeps draws readable. 2 mL gives 10 mg/mL and doubles the mass per unit.
Should I use the blend or separate vials?
Separate vials if the protocol needs independent dosing of each compound. The blend if both mechanisms are wanted together at equal mass and one reconstitution is preferable.
How long does a 20 mg blend last?
At a 20-unit draw daily (500 mcg of each), 100 units per mL at 5 mg/mL means 20 mg covers 40 days of daily draws — beyond the 28-day window, so size down if you dose daily. See how long BAC water is good for.
Related: the composition and ratio questions are covered in the BPC-157 and TB-500 blend guide.
Wolverine Blend, Priced Per Vial
10 mg $50 · 20 mg $90 — $5.00 and $4.50 per milligram, with the per-compound split printed on the listing and the batch number matched to the published certificate. View the Wolverine Blend →Premium Collection
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