Shuttles fat into the cell’s furnace so it can actually get burned. Helpful when you’re in a calorie deficit or training a lot.
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Research & reference information
This profile compiles research and community-sourced reference information for educational purposes. Information may evolve as research and community knowledge develop. It is not individualized medical advice.
Overview
Shuttles fat into the cell’s furnace so it can actually get burned.
Helpful when you’re in a calorie deficit or training a lot.
What It Does
Amino acid derivative essential for mitochondrial fatty acid transport.
Injectable provides 5–10× higher plasma levels than supplement intake.
Transfers long-chain fatty acids across the inner mitochondrial membrane via CPT1/CPT2 carnitine shuttle.
Reconstitution
Vial Size
BAC Water / Solvent
Concentration
600 mg
+ 0.60 mL
1000 mg/mL
1200 mg
+ 1.2 mL
1000 mg/mL
Interactive tool
Reconstitution Calculator
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Optional conversion
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Protocol
Phase
Frequency
Amount
Notes
Standard
M/W/F
500–1,000 mg
Community dose.
High
M/W/F
1,200–1,500 mg
Fat oxidation range.
Pre-WO
Before exercise
500 mg
Timing-specific.
Cycle & Timing
8–12 weeks on / 4 weeks off. Max: ongoing maintenance with quarterly 2-week breaks.
Timing
Pre-workout (preferred, 30–60 min before) or daily anytime.
Population Considerations
Unisex fat-metabolism cofactor, same protocol for men and women; no meaningful sex difference. Generally well tolerated.
Handling & Stacking
Injection site
IM preferred or SubQ. Upper outer thigh for volume.
Storage
Freeze-dried: -4°F.
Reconstituted: 36–46°F.
Best used within 28 days.
There's no real community potency figure here; L-carnitine's a stable small molecule, so the honest limit on a reconstituted multidose vial is sterility at ~28–30 days refrigerated, not potency.
Side effects
Fishy odour (TMAO conversion). Generally well tolerated.
What to expect
Exercise performance and fat utilisation improvement within 2–4 weeks.
Reduced post-workout fatigue.
Works best in caloric deficit or with GLP- 1 therapy.
Hypothyroid medication, separate by 4 hrs. Warfarin (may potentiate)
Safety & Patient Education
Contraindications
Component allergies (B12, riboflavin, lecithin, choline, methionine, lidocaine) Hypothyroid medication, separate by 4 hours Severe hepatic impairment (choline metabolism) Pregnancy and lactation, specific compounding required Bleeding disorders or anticoagulants (relative), bruising risk Severe renal impairment (carnitine accumulation) Seizure disorder (case reports of seizure exacerbation) Hypothyroidism without dose separation
Warnings
Compounded products, composition varies; request the pharmacy’s COA B12 (cyanocobalamin) contains cobalt, allergy possible Methionine elevates homocysteine in some individuals L-Carnitine: TMAO conversion concern in CV disease (controversial, baseline lipids) Injection-site reactions common with phosphatidylcholine
Drug interactions
Warfarin: L-carnitine and choline blends can potentiate, monitor INR if combining Levothyroxine: separate by 4 hours, choline/B-vitamins affect absorption Anticoagulants / antiplatelets (DOACs, aspirin, clopidogrel): bruising risk with phosphatidylcholine Insulin / antidiabetics: B-complex may shift glucose, recheck log if dosing changes Methotrexate, trimethoprim, phenytoin: deplete folate / B12; coordinate with prescriber Lidocaine blends (LC526): avoid other caines same session, additive cardiac effects Stimulants / phentermine: additive CV load with high-dose lipotropics, monitor BP/HR Warfarin (potentiation), thyroid medication (separate by 4 hours)
Fishy odor from choline/L-carnitine is normal, not allergic Inject slowly to reduce stinging Don’t use with warfarin without physician guidance (potentiation risk) Request exact ingredient list and concentrations from your compounder
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