A short peptide bioregulator (Khavinson) aimed at the brain. Proposed to support cognition, neuroprotection, and healthy sleep/circadian regulation in brief courses; the brain-targeted member of the bioregulator family.
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Research & reference information
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Overview
A short peptide bioregulator (Khavinson) aimed at the brain.
Proposed to support cognition, neuroprotection, and healthy sleep/circadian regulation in brief courses; the brain-targeted member of the bioregulator family.
What It Does
Pinealon is a Khavinson tripeptide (Glu-Asp-Arg, EDR) targeting brain tissue.
It is proposed to support neuronal gene expression, protect against oxidative/excitotoxic stress, and aid cognition and circadian regulation.
Evidence is largely from Russian research; short pulsed courses.
Reconstitution
Vial Size
BAC Water / Solvent
Concentration
5 mg
+ 2.5 mL
2 mg/mL
10 mg
+ 5 mL
2 mg/mL
Interactive tool
Reconstitution Calculator
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Protocol
Phase
Frequency
Amount
Notes
Course (10–20 days)
Daily
1–2 mg SubQ (up to 10 mg)
SubQ, daytime. Some protocols run higher single doses.
Between courses
–
–
1–3 courses per year.
Cycle & Timing
10–20 day course, 1–3×/year.
Timing
daytime (may be mildly activating). Note: brain-targeted bioregulator; evidence is largely Russian research.
Population Considerations
Unisex peptide bioregulator, short courses, no sex-specific dosing; minimal human data. Avoid in pregnancy.
Handling & Stacking
Injection site
SubQ, abdomen. Rotate.
Storage
Freeze-dried: -4°F. Reconstituted: 36–46°F, best used within ~4–6 weeks (structure-based estimate), which covers the usual course.
Side effects
Generally well tolerated, mild injection-site reaction; possible mild activation if dosed late. Limited human data.
What to expect
Proposed cognitive/neuroprotective support over a course; subtle, preliminary evidence. Supply math 5mg → 8 vials | 10mg → 4 vials (20-day course @ 2 mg/day SubQ)
Active malignancy (theoretical gene-expression effects). Pregnancy
Safety & Patient Education
Contraindications
Active malignancy (theoretical, tissue gene-expression modulation) Pregnancy and lactation Hypersensitivity to the peptide
Warnings
Limited Western clinical data, most evidence is Russian research Mild activation possible, dose earlier in the day Quality varies, request a COA
Drug interactions
No well-characterized interactions Commonly stacked with other bioregulators / nootropic peptides
Labs
None compound-specific; cognitive tracking if that’s the goal
Stop criteria
Persistent injection-site reaction or sleep disruption Any unexpected neurological symptom Pregnancy
Patient education
A short-course, brain-targeted bioregulator; not continuous Dose earlier in the day to protect sleep Evidence is preliminary and largely Russian Request a COA; source quality matters
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