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PINEALON

A short peptide bioregulator (Khavinson) aimed at the brain. Proposed to support cognition, neuroprotection, and healthy sleep/circadian regulation in brief courses; the brain-targeted member of the bioregulator family.

Research referenceCommunity compiled

Molecular profile

The molecule itself: sequence, composition, mass, target, and registry identifiers.

Amino acid sequence

EDR
3 residues
Molecular formula
C₁₅H₂₆N₆O₈
Average mass
418.40 Da
CAS number
175175-23-2
Registry
PubChem CID 10273502
Receptor / pathway
Chromatingene expression
Formula, mass and identifiers from PubChem CID 10273502. Mass recomputed from the sequence.
Research & reference information

This profile compiles research and community-sourced reference information for educational purposes. Information may evolve as research and community knowledge develop. It is not individualized medical advice.

Overview

Pinealon (EDR) is a synthetic short-chain tripeptide bioregulator designed specifically to support the brain, central nervous system, and cognitive longevity.

What problem it targets: It targets brain fog, poor memory retention, mental fatigue, age-related cognitive decline, traumatic brain injury recovery, and sleep-wake cycle disruption.

What It Does

• Restores neuronal protein synthesis: Penetrates the blood-brain barrier and cell nuclei to interact with DNA, stimulating the synthesis of essential structural and functional brain proteins.

• Exerts potent neuroprotection: Protects cortical neurons against hypoxia, oxidative stress, and free radical damage, preventing premature neuronal apoptosis.

• Optimizes cognitive stamina and focus: Enhances neurotransmitter efficiency and mental processing speed during intense psychological or intellectual stress.

• Realistic expectations: Administered in short 10- to 20-day cycles a few times per year. Enhances mental clarity and focus without the jitters, crashes, or addiction risks of classic stimulants.

Reconstitution

Vial sizeBAC water / SolventConcentration
5 mg+ 2.5 mL2 mg/mL
10 mg+ 5 mL2 mg/mL

Protocol

PhaseFrequencyDoseUnits (2 mg/mL)Notes
Course (10–20 days)Daily1–2 mg SubQ (up to 10 mg)50–100uSubQ, daytime. Some protocols run higher single doses.
Between courses–––1–3 courses per year. Cycle: 10–20 day course, 1–3×/year. Timing: daytime (may be mildly activating). Note: brain-targeted bioregulator; evidence is largely Russian research. By sex: Unisex peptide bioregulator, short courses, no sex-specific dosing; minimal human data. Avoid in pregnancy.

Handling & Stacking

Injection site
SubQ, abdomen. Rotate.
Storage
Freeze-dried: -4°F. Reconstituted: 36–46°F, best used within ~4–6 weeks (structure-based estimate), which covers the usual course.
Side effects
Generally well tolerated, mild injection-site reaction; possible mild activation if dosed late. Limited human data.
What to expect
Proposed cognitive/neuroprotective support over a course; subtle, preliminary evidence. Supply math 5mg → 8 vials | 10mg → 4 vials (20-day course @ 2 mg/day SubQ)
Pairs well with
Semax / Selank / P21 (cognition); Epithalon (pineal/longevity); other Khavinson bioregulators
Avoid
Active malignancy (theoretical gene-expression effects). Pregnancy

Safety & Patient Education

Contraindications
Active malignancy (theoretical, tissue gene-expression modulation) Pregnancy and lactation Hypersensitivity to the peptide
Warnings
Limited Western clinical data, most evidence is Russian research Mild activation possible, dose earlier in the day Quality varies, request a COA
Drug interactions
No well-characterized interactions Commonly stacked with other bioregulators / nootropic peptides
Labs
None compound-specific; cognitive tracking if that’s the goal
Stop criteria
Persistent injection-site reaction or sleep disruption Any unexpected neurological symptom Pregnancy
Patient education
A short-course, brain-targeted bioregulator; not continuous Dose earlier in the day to protect sleep Evidence is preliminary and largely Russian Request a COA; source quality matters
References
researchdosing · peptidedosages · PubMed · thepeptidereport